MicroRNA detection based on analyte triggered nanoparticle localization on a tetrahedral DNA modified electrode followed by hybridization chain reaction dual …
We have constructed an ultrasensitive method for microRNA detection based on analyte
triggered nanoparticle localization and hybridization chain reaction dual amplification. The
limit of detection is 2 aM. Furthermore, the applicability of this method for microRNA assay in
real samples is demonstrated by the analysis of cell lysates.
triggered nanoparticle localization and hybridization chain reaction dual amplification. The
limit of detection is 2 aM. Furthermore, the applicability of this method for microRNA assay in
real samples is demonstrated by the analysis of cell lysates.
We have constructed an ultrasensitive method for microRNA detection based on analyte triggered nanoparticle localization and hybridization chain reaction dual amplification. The limit of detection is 2 aM. Furthermore, the applicability of this method for microRNA assay in real samples is demonstrated by the analysis of cell lysates.
The Royal Society of Chemistry