Cell penetrating peptides: efficient vectors for delivery of nanoparticles, nanocarriers, therapeutic and diagnostic molecules

SM Farkhani, A Valizadeh, H Karami, S Mohammadi… - Peptides, 2014 - Elsevier
Efficient delivery of therapeutic and diagnostic molecules to the cells and tissues is a difficult
challenge. The cellular membrane is very effective in its role as a selectively permeable
barrier. While it is essential for cell survival and function, also presents a major barrier for
intracellular delivery of cargo such as therapeutic and diagnostic agents. In recent years, cell-
penetrating peptides (CPPs), that are relatively short cationic and/or amphipathic peptides,
received great attention as efficient cellular delivery vectors due to their intrinsic ability to …